gearTRiNDS – Therapeutic Research in Neuromuscular Disorders Solutions, is a newly formed contract research organization (CRO) born from the CINRG academic consortium, providing solutions to pharmaceutical and biotechnology industries as well as academic investigators/groups for their neuromuscular clinical study needs. Our solutions are in these four key pillars:

Clinical Operations


TRiNDS Clinical Operations offers trial management solutions throughout all stages of a clinical trial and for Phase I through Phase IV (post marketing). TRiNDS Clinical Operations has a dedicated and passionate team of project managers with specialized neuromuscular clinical trial management experience. The team provides comprehensive oversight for protocol design, protocol feasibility, overall protocol compliance and monitoring. As the official Coordinating Center for CINRG, TRiNDS also runs the independent CINRG Data and Safety Monitoring Board (DSMB).

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Data Management


TRiNDS data managers are specialized in neuromuscular and rare diseases TRiNDS provides full service data management support and offers OpenClinica as its electronic data capture (EDC) system. The data management team can help from database design all the way through to data lock in a timely manner.

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TRiNDS biostatisticians and statistical programmers offers expertise in neuromuscular disorder, rare diseases statistics, and regulatory best-practices to help with a broad scope of biostatistics and programming services. Through the oversight of two of its board members, Dr. Avital Cnaan and Dr. Heather Gordish-Dressman, and as the official Coordinating Center for CINRG, TRiNDS can perform analyses and data matching protocols from the CINRG Duchenne Natural History Study.
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Study Measurements

TRiNDS offers a broad range of expertise to help select the most appropriate study measurements across the entire neuromuscular disease spectrum from biomarkers, strength and function, pulmonary, cardiac, to patient reported outcomes. Our team provides training and management throughout the duration of the study. As the official Coordinating Center for CINRG, TRiNDS can use the CINRG quantitative measurement system which is integrated into our Data Management solutions. It also builds on the CINRG consortium expertise with the CINRG Duchenne Natural History for the selection of study endpoints.
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