Board


  • Avital Cnaan

    Ph.D.

    Dr. Avital Cnaan is a co-founder of TRiNDS and has served as a member of our board since May 2016.
  • Paula Clemens

    M.D.

    Dr. Paula Clemens is a clinician and scientist at the University of Pittsburgh, and has served as a member of our board since December 2016.In addition to her university-based practice and research efforts, she directs the in-patient and out-patient neurology clinical teaching service at the VA Pittsburgh Healthcare System. She has particular expertise in the care of adults with neuromuscular diseases such as Duchenne and Becker muscular dystrophy, myotonic dystrophy and spinal muscular atrophy. She has further expertise in the management and enzyme replacement treatment of patients with late-onset Pompe disease. In addition to providing clinical care for patients with a broad array of neurological problems, she pursues both clinical and basic translational research focused on the development of treatments for genetic muscle diseases. In this context, she has trained PhD candidates, post-doctoral fellows and medical students. She is the Medical Director of an academic clinical trial network for muscle disease research that has study sites worldwide, the Cooperative International Neuromuscular Research Group (CINRG). She leads several multi-center studies focused on the natural history of and drug development for genetic muscle diseases. By partnering with advocacy and research groups globally, Dr. Clemens and colleagues have contributed to the development of outcome measures with utility for all muscle disease therapeutics research.
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  • Heather Gordish-Dressman

    Ph.D.

    Dr. Heather Gordish-Dressman is a co-founder of TRiNDS and has served as a member of our board since May 2016. She is the current President of the board.

    Dr. Gordish-Dressman is an Assistant Professor of Pediatrics and Integrative Systems Biology at George Washington University School of Medicine and Health Sciences and in the Center for Genetic Medicine Research at Children's National Medical Center. Dr. Gordish-Dressman has worked with Dr. Eric Hoffman and served as the primary statistician for the Center for Genetic Medicine Research since 2002.  She specializes in the analysis of various types of genetic data including large-scale cohort studies, proteomic data, microarray data and single nucleotide polymorphism data in both candidate gene and GWAS studies.  She has served as the statistician for Dr. Kanneboyina Nagaraju’s Pre-clinical Murine Testing Facility at CNMC and continues this work as a consulting statistician for AGADA BioSciences.  Since 2010, Dr. Gordish-Dressman has provided statistical support to the Cooperative International Neuromuscular Research Group (CINRG) under the direction of Dr. Cnaan.  Here she focused on the analysis of natural history studies and facilitated collaborations with academic and industry partners.  Dr. Gordish-Dressman has provided statistical support to a large number of collaborators both within CNMC and at other institutions around the world.  She has co-authored 100 scientific publications on a wide variety of topics including, Duchenne muscular dystrophy, cerebral palsy, asthma, necrotizing enterocolitis, biomarkers of disease and drug treatment, obesity and metabolic traits, and muscle strength and fitness.


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  • Eric Hoffman

    Ph.D.

    Dr. Eric Hoffman is a co-founder of TRiNDS and has served as a member of our board since May 2016. He is the current Secretary of the board.

    Dr. Hoffman is a human geneticist and translational researcher focused on neuromuscular disease, and skeletal muscle tissue in health and disease.  His most recent efforts focus on drug development and clinical trials in Duchenne muscular dystrophy. He received his PhD in Drosophila molecular genetics from Johns Hopkins University, then carried out a post-doctoral fellowship at Boston Children’s Hospital and Harvard Medical School working on the identification of the DMD gene and protein. His current academic positions are Associate Dean for Research, School of Pharmacy and Pharmaceutical Sciences, Binghamton University – SUNY, where he is building a research program focused on facilitating drug development at the academic/industry interface.  In the private sector, he is co-founder and CEO of ReveraGen Biopharma and co-founder and Vice President of AGADA Biosciences.  He serves on Scientific Advisory Boards of Foundation to Eradicate Duchenne, CureDuchenne Foundation, C3 Foundation, Save Our Sons Foundation, and Duchenne UK. Research accomplishments include identification of the dystrophin protein, and defining its deficiency in DMD patient muscle, mdx mouse, dog and cat models. His lab identified initial voltage sensitive ion channel mutations in human disease, and genetic causes of recurrent pregnancy loss. He is an inventor on nine patents, and has authored over 500 publications.


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