February 3, 2021
TRiNDS Genetic Confirmation Services
There are many different types of muscular dystrophies, each caused by different types of genetic mutations. The genetics of muscular dystrophies and other rare neuromuscular disorders are difficult to understand and important to get right for clinical trials. Some are caused by a variation in a gene or group of genes and others can be assigned subtypes by presence of certain variations. Even among people with the same diagnosis, they might have different genotypes from each other – which can make the difference between being eligible or ineligible for a clinical trial. It is critical to confirm eligibility for a clinical trial consistently across sites and regions. It’s essential to record the genotype correctly across sites so trial analysis can explore possible effects of different genotypes on study results.
TRiNDS Genetic Confirmation offers central review of genetic testing results for rare neuromuscular disease trials and research studies. Our team of in – house licensed genetic counselors leverage past experience in Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), Pompe Disease, and other neuromuscular disorders. Our genetic counselors work with sponsors throughout trial planning and execution. Our team can help you design protocols, set up study procedures for central review, and collaborate with data management to properly capture the genetic data in your electronic data capture systems.
TRiNDS offers central expert genetic confirmation services to sponsors conducting clinical trials throughout the development process. We customize services to each project to meet its unique needs. Contact us for more about how TRiNDS can help your project succeed.